Ketorolac Tromethamine

Ketorolac Tromethamine: use, side effects and contraindications

Ketorolac tromethamine is an anti-inflammatory drug belonging to the group of pyrrolizine carboxylic acid derivatives. The international name of the drug is ketorolac. It is used to treat moderate to severe pain, including post-operative pain, joint pain from ligamentous injuries, sprains, sprains, back pain and muscle pain.

The drug is manufactured in India by the pharmaceutical company Lupine Laboratories and is available in the form of a substance. The active substance is ketorolac.

However, before starting treatment with ketorolac, you should pay attention to contraindications to its use. This is hypersensitivity (including to aspirin and other NSAIDs), nasal polyps, angioedema, bronchospasm, bronchial asthma, gastric and duodenal ulcers, impaired renal function, hypovolemia, dehydration, high risk of postoperative bleeding or incomplete stopping of bleeding, impaired hematopoiesis , cerebral hemorrhage, pregnancy, breastfeeding (breastfeeding must be stopped during treatment) and early childhood (up to 2 years).

Side effects may occur when using ketorolac. These may include dry mouth, dyspepsia, gastrointestinal pain, nausea, vomiting, diarrhea, fullness, peptic ulcers, gastritis, liver dysfunction, flatulence, black stool, constipation, rectal bleeding, stomatitis, headache, pallor, dizziness, nervousness, depression, drowsiness, asthenia, sweating, edema, dyspnea, bronchial asthma, impaired taste and vision, vasodilation, increased urination, oliguria, glomerulonephritis, nephrotic syndrome, acute renal failure, myalgia, urticaria, itching, purpura, pain at the injection site.

You should also consider the possible interaction of ketorolac with other drugs. Incompatible with lithium preparations, pentoxifylline, probenecid, anticoagulants (in high doses) and other NSAIDs. In addition, ketorolac reduces the effect of diuretics and antihypertensive drugs, which can worsen the patient's condition.

When using ketorolac, you must take precautions and not exceed the recommended dose, as this can lead to serious complications. It is also not recommended to use ketorolac for a long time, as this can cause the development of stomach ulcers and other gastrointestinal complications.

In general, ketorolac is an effective anti-inflammatory drug, but its use should be limited only as prescribed by a doctor and taking into account contraindications and possible side effects.