Quinine

Kinins are a group of biologically active substances that are formed in the human body and play an important role in the regulation of many physiological processes. These polypeptides are active vasodilators and are capable of lowering blood pressure, as well as causing relaxation of the smooth muscles of blood vessels and internal organs.

Kinins are formed as a result of the proteolytic cleavage of certain globulin proteins in the blood plasma, called kininogens. In this case, active peptide chains are formed, among which the most important are bradykinin and kallidin. Bradykinin is one of the most active kinins, it is involved in the regulation of blood pressure, affects heart rate, dilates blood vessels, reduces inflammation and stimulates the immune system.

However, kinins can also be harmful to the body if their levels in the blood become too high. In this case, they can cause various diseases, for example, hypertension, bronchial asthma, migraines, heart attacks and others. Therefore, it is important to monitor the level of kinins in the blood and take measures to regulate them.

In general, kinins play an important role in maintaining the health of the body and regulating many of its functions. However, if kinins are used incorrectly or in excess, serious health problems can occur. Therefore, it is necessary to know about the action of kinins and take measures to regulate them.

Kinins are biologically active peptides that are formed in the human body and play an important role in the regulation of various physiological processes. Kinins are members of a group of polypeptides and have the ability to relax smooth muscles and lower blood pressure.

Kinins are formed as a result of the action of proteolytic enzymes on certain blood plasma proteins - kininogens. When tissue is damaged, or changes in blood acidity or temperature, kininogenesis can occur, leading to the formation of kinins.

One of the most well-known forms of kinins is bradykinin, which is formed in the blood when tissue is damaged and is involved in the regulation of blood pressure and relaxation of vascular smooth muscle. Callidin is also an active kinin that is involved in the regulation of blood pressure and is involved in inflammatory processes.

Although kinins play an important role in the body, they can also be harmful in certain situations. For example, with an excess of kinins in the blood, hypersensitivity may occur, which can lead to various diseases. Therefore, it is important to control the level of kinins in the body and maintain it at an optimal level.

Kinins are a group of polypeptide hormones that play an important role in the regulation of various physiological processes. They are widely distributed in the body and have been studied for many years. In this article we will look at what kinins are and what their mechanism of action is.

Kinins are polypeptide hormones that are formed from blood plasma as a result of the action of protamine hydrolase enzymes (proteolytic enzymes). These enzymes catalyze the cleavage of the kinin polypeptide chain, allowing the release of its peptide tail. Once the tail is released, kinin interacts with receptors in many tissues, causing a number of biochemical changes.

There are several types of kinins, the best known of which are kallidin and bradykinin. Callidin is released from mast cells and causes dilation of blood vessels, and bradykinin, which has an affinity for the RAH-1, RAH-2, and RA6 receptors, has a potent vasodilatory effect. Bradykinin can also cause the release of histamine from mast cells, which leads to dilation of blood vessels. Thus, kinins play an important role in many functional processes.

Many diseases are associated with the activity of kinins. For example, prostaglandins produced by bradykinin can cause inflammation and swelling. Likewise, kallidin causes vasodilation, which can lead to anemia and hypoxia in tissues. It is a potential cause of anemia associated with certain diseases such as bronchiectasis.

A number of medical conditions are also associated with changes in kinin activity in the body. There are various drugs containing proteases, such as papaverine and pancuron. Their use may result in increased bradykinin levels and edema, which are possible side effects. In addition, some neuro