Reed-Sternberg cell (Reed-Stemberg Celt)

The Reed-Sternberg cell is a giant multinucleated cell characteristic of Hodgkin lymphoma. These cells were first described in 1902 by American pathologists Dorothy Reed and Carl Sternberg, after whom they received their name.

Morphologically, Reed-Sternberg cells are large, often contain two or more nuclei, and have a characteristic “owl's eye” appearance due to the presence of inclusions in the cytoplasm that give it a basophilic color. These giant tumor cells originate from B lymphocytes and are diagnostic of classical Hodgkin lymphoma. Detection of Reed-Sternberg cells allows pathologists to make the correct diagnosis and prescribe adequate treatment for this disease.

A Reed-Sternberg cell, also known as a Sternberg-Reed cell, is a type of tumor cell that is usually found in lymph nodes. These cells were first described in 1898 by scientists Reed and Sternberg while researching a disease known as lymphogranulomatosis.

Reed-Sternberg cells are large, multinucleated cells that have an unusual spider-like shape. They are often surrounded by lymphocytes and other cells of the immune system.

Although Reed-Sternberg cells were first discovered in association with lymphogranulomatosis, they can also be found in other types of lymphomas. In some cases, their presence can help in diagnosing the disease.

However, the role of Reed-Sternberg cells in the development of lymphoma is still not fully understood. Some studies suggest that these cells may play a role in protecting the body from infections, while others suggest that they may stimulate the growth of malignant cells.

Thus, although Reed-Sternberg cells continue to be the subject of research and debate in the scientific community, they represent an important element in understanding the various types of lymphomas and can help in the diagnosis and treatment of these diseases.