Climatopathological Reaction

Climatopathological reactions (CPR) are a specific island-like damaging reaction of the body that develops in response to changing climatic conditions and is characterized by local temperature discomfort, dysfunction of organs and systems, and vegetative-vascular disorders.

The determining reason for the development of CPR is a change in thermoregulation processes under the influence of external microclimatic factors. The higher the ambient temperature, the less evaporated moisture on the skin, which leads to increased water loss in the body, impaired heat transfer, shortness of breath, tachycardia, circulatory failure, decreased blood pressure, a feeling of thirst, and sometimes headaches with arterial hypotension. and cold extremities. When the external temperature decreases, a reverse development of pathological changes occurs: a feeling of chills, a decrease in the temperature of the extremities, but the internal body temperature rises, the blood supply to the internal organs is activated, a feeling of weakness quickly develops, and the heart rate increases. The condition of the body is aggravated by exposure to contagious external factors (infectious diseases), an increase in fatigue, exhaustion in a person, in some cases (with severe climate change) against the background of premorbid characteristics of the body (weakening of the nervous system). The development of CPR is accompanied by a violation of the metabolism and adaptive abilities of the body in response to the influence of natural factors, leading to an acceleration of the rate of free radical lipid peroxidation with hyper