Platelet cofactor

Thrombin cofactor (thromboxane A2) is a biologically active substance that is formed during platelet aggregation. It is involved in the cascade of reactions required to convert fibrinogen to fibrin. Physiologically appears only after damage to the vessel wall. Its appearance is associated with the formation of active forms of platelets that contain platelet A2, an aggregation cofactor that promotes the formation of a blood clot. Active forms of platelets appear during hemostasis in the form of a precipitate, which is formed after exposure to irritants on the wall of a blood vessel. Platelet aggregation in the hemoplasm occurs without chemical or mechanical influences. In this case, the platelets do not merge, but rather become saturated and increase the area of ​​interaction with each other.

The blood vessel is coated with a special protein - collagen, which performs two functions. The first is to ensure the attachment of blood cells to the wall of the vessel, and the second is to limit their mobility, then