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Cordanum 50: Beta1-blockers for the cardiovascular system

Cordanum 50, also known as Talinolol, is a pharmacological drug belonging to the group of cardioselective beta1-blockers. It is widely used in the treatment of various cardiovascular diseases. Cordanum 50 is produced by the German pharmaceutical company Arzneimittelwerk Dresden GmbH.

Cardioselective beta1-blockers act on the receptors of the beta1-adrenergic system, which are located mainly in the heart. They block the action of epinephrine and norepinephrine on these receptors, resulting in a decrease in heart rate, contraction force, and cardiac contractility. This reduces the load on the heart and lowers blood pressure.

Cordanum 50 is used for various cardiovascular diseases. It is effective in the treatment of angina pectoris (tension, unstable), acute myocardial infarction (in treatment and prevention), arterial hypertension, diastolic heart failure, supraventricular and ventricular extrasystole, paroxysmal tachycardia, atrial flutter and fibrillation, hyperkinetic cardiac syndrome and neurocirculatory dystonia of the hypertensive type .

However, Cordanum 50 also has contraindications. Its use is not recommended in case of hypersensitivity to the drug, cardiogenic shock, severe bradycardia (less than 50 beats per minute), impaired AV conduction and sinoauricular conduction, sick sinus syndrome, heart failure (NYHA grade III-IV) with reduced systolic function of the left ventricle, acute myocardial infarction with complications, severe hypotension, bronchial asthma, decompensated diabetes mellitus and breastfeeding. You should also limit the use of Cordanum 50 in case of obstructive pulmonary diseases, impaired renal function, severe disorders of the peripheral arterial circulation, Prinzmetal's angina, AV block of the first degree, pheochromocytoma, labile diabetes mellitus, metabolic acidosis, a burdened allergic history, psoriasis, and Cordanum 50 has some side effects that may occur when using it. They include bradycardia (slow heart rate), dizziness, fatigue, drowsiness, decreased blood pressure, cold extremities, edema, sleep disturbances, depression, bronchospasm (in patients with bronchial asthma), decreased potency, gastrointestinal disorders (nausea, vomiting) , diarrhea, constipation), allergic reactions and others.

It is important to note that the use of Cordanum 50 should be carried out only as prescribed by a physician, and the dosage should be individualized depending on the characteristics of the patient and the characteristics of the disease.

Patients taking Cordanum 50 should undergo regular medical monitoring and follow the doctor's recommendations. Sudden cessation of the drug may cause withdrawal symptoms, so the dosage should be reduced gradually under the supervision of a physician.

Overall, Cordanum 50 is an effective and widely used drug for the treatment of cardiovascular diseases. However, the decision to use it must be made by a physician, and patients must carefully follow the directions and recommendations to minimize risks and achieve maximum benefit from treatment.