Corvette

Korvert: Antiarrhythmic agent that slows repolarization

Corvert, whose international name is ibutilide, is an antiarrhythmic drug used to relieve attacks of atrial flutter or atrial fibrillation. It belongs to the pharmacological group of antiarrhythmic drugs that slow down repolarization. Corvert is manufactured by the pharmaceutical company Pharmacia in the United States of America.

The dosage form of Corvert is a solution for infusion containing 0.087 mg/ml of the active substance ibutilide. This drug must be used under the supervision of a cardiologist because it affects cardiac activity and may cause certain side effects.

Korvert has several contraindications. It is not recommended for patients with hypersensitivity to ibutilide, as well as for women during pregnancy and breastfeeding. Before starting to use Corvert, you should consult your doctor and make sure that there are no contraindications to its use.

Some side effects may occur when using Corvert. These may include bradycardia (slowing the heart rate), tachycardia (accelerating the heart rate), palpitations, conduction disturbances in the AV system (connecting the atria and ventricles) of the heart, arterial hypotension (lowering blood pressure), extrasystoles (additional contractions of the heart), ventricular and supraventricular arrhythmias, blood pressure changes, nausea, headache and renal failure.

You should also pay attention to possible interactions of Corvert with other drugs. With the simultaneous use of drugs that prolong the QT interval (electrocardiographic indicator), there is a risk of an additive increase in the duration of the QT interval and the development of ventricular arrhythmia of the "pirouette" type. Therefore, it is important to tell your doctor about all the medications you are taking to avoid unwanted interactions.

There is no specific information available regarding overdose of Corvert. However, if you take too much of the drug, you should seek medical help.

In conclusion, Corvert is an antiarrhythmic drug used to relieve attacks of atrial flutter or atrial fibrillation. It can cause various side effects and interact with other medications, so its use should be under the supervision of a cardiologist. It is important to follow all doctor’s instructions and not exceed the recommended dose of the drug.

Source: Vidal Handbook 2006