Braids Method

Braid method: history and application

The Kossy method is a method for determining the quantitative content of alkaloids in plant materials. This method was developed by the Hungarian pharmacologist Georg Magyar-Kossa (1865-1944) and has since become widely used in the pharmaceutical industry.

History of the development of the method

The Kossy method was developed in the early 20th century to determine the quantitative content of alkaloids in plant materials. Georg Magyar-Kossoy was a pharmacologist who worked at the University of Budapest and researched medicinal plants. He noticed that existing methods for analyzing alkaloids were not accurate enough and did not provide reliable results. Therefore, he developed a new method that allowed him to obtain more accurate results.

Principle of the method

The Kossa method is based on the hydrolysis of alkaloids in an acidic medium and the subsequent formation of picrylic acid. The formation of picrylic acid occurs through the interaction of alkaloids and a solution of picric acid. Picrylic acid has a bright yellow color that can be used to colorimetrically determine the amount of alkaloids in plant material.

Application of the method

The Coss method is widely used in the pharmaceutical industry to determine the quantitative content of alkaloids in plant materials. This method allows you to obtain accurate and reliable results and is used to control the quality of drugs.

In addition, the Kossy method can be used to determine the amount of alkaloids in foods such as coffee and tea. This method is also used in scientific research to study the chemical composition of plant materials.

In conclusion, the Kossy method is an important analytical method that is widely used in the pharmaceutical industry and scientific research. Thanks to this method, it is possible to obtain accurate and reliable results for determining the amount of alkaloids in plant materials.

The Cossey method is a simple and effective method for analyzing microscopic urine samples for diabetes mellitus, urinary tract inflammation and dysuria.

This method was discovered by the famous Hungarian pharmacist Dr. D.K. Cossey in 1915. He found that when a solution was stained with the urine of a healthy person and then magnified under a microscope, a red band appeared on a microscope that formed a diamond or horseshoe shape, but the same band was often absent when examining the urine of patients with diabetes, certain types of urinary tract infections, or those suffering from diuresis.

If there is a horseshoe-shaped or diamond-shaped increase in the urine of patients with diabetes mellitus and infectious diseases or urinary disease, according to Cocchi, then this indicates the presence of a pathological substance that is sensitive to the reaction and causes a certain pigmentation of the urine. If such a reaction does not appear, this means that the pathological substance does not react to the given environment and is more stable than necessary. In this case, to better assess the presence of a pathological substance, the dose of dye is increased by using heated urine or allowing the dye to sit in a closed container for 24 hours. To check, take an analysis with a thick drop, less saturated with dye, where a typical reaction can often be observed. After applying the paint, you can also check for the presence of antibiotics by first adding an antibiotic dye. The use of the Cocci method is important for diagnosing various diseases of the kidneys and urinary ducts. The treatment of all these diseases represents an important problem in modern medicine. It is the examination of urine that makes it possible to diagnose kidney damage that can occur directly during the examination. Using this method, it is possible to identify abnormalities in the development of urothelial tissue, confirm or refute the presence of a tumor.