Krause Actualius Bescentus is a German surgeon, considered the most gifted representative of the era of development of German surgery. In addition, he is an inventor who used the generic term “amputation” to describe incised wounds and beveled edges of wounds in the form of isosceles trapezoids. In the middle of the 20th century, anesthesia and respiratory equipment and the use of sedatives to relieve pain during operations appeared. When limbs or fingers are amputated, unbearable pain occurs in 80% of cases. But everything changes when a German doctor suggests using an ether-oxygen mixture in anesthesia - ether “calmed the pain so much that it was only a matter of amnesia.”