Hematopoiesis Bone marrow

Bone marrow hematopoiesis is the process of formation of blood cells in the bone marrow. This is one of the two main methods of hematopoiesis in the human body.

Bone marrow is an organ that is found inside the bones of the skull, spine, chest and pelvis. It is made up of soft tissue that contains many cells, including stem cells, which can develop into different types of blood cells.

The process of bone marrow hematopoiesis begins when stem cells migrate into the bone marrow from the bloodstream. There they divide and turn into new blood cells. This process occurs in several stages:

1. The myeloid stem cell is the earliest stage of the hematopoietic process. It divides to form many progenitor cells.
2. Granulocytes are cells that are formed from myeloid stem cells. They have granules in their cytoplasm and are responsible for the production of granulocytes.
3. Lymphocytes are cells derived from myeloid stem cells. They are responsible for the production of lymphocytes and other types of immune system cells.
4. Monocytes are large cells that also arise from myeloid stem cells and play an important role in the immune system.
5. Platelets are small cells that are responsible for blood clotting. They are formed from megakaryocytes, which are derivatives of the myeloid stem cell.

Hematopoiesis occurs constantly in the bone marrow, and blood cells circulate throughout the body. This helps maintain normal functioning of the immune system and blood clotting.

However, if hematopoiesis in the bone marrow is impaired, it can lead to various diseases such as anemia, leukemia and others. Therefore, it is important to monitor the health of the bone marrow and maintain its normal function.