Lactacidemia

Lactacidemia is a pathological condition characterized by an increased level of lactic acid in the blood.

Lactic acid is formed in the body during anaerobic glycolysis and is normally effectively metabolized in the liver and kidneys. When this process is disrupted, excessive accumulation of lactic acid in the blood occurs.

Causes of lactic acidemia:

1. Tissue hypoxia in shock, acute cardiovascular or respiratory failure

2. Intense physical activity

3. Inborn errors of metabolism

4. Taking biguanides and alcohol

5. Oncological diseases

Clinical manifestations:

1. Tachycardia, hypotension

2. Dyspnea

3. Stomach ache

4. Nausea, vomiting

5. Impaired consciousness

Diagnosis is based on determining high levels of lactic acid in the blood.

Treatment depends on the cause and includes: elimination of hypoxia and shock, hemodialysis, administration of sodium bicarbonate.

Thus, lactic acidemia is a dangerous complication of many critical conditions, requiring timely diagnosis and adequate treatment.

Lactacidemia is a pathological condition of the body as a result of excess lactic acid in the blood, which causes serious disruption of the functioning of internal organs and systems. Lactacidemia is also called hypolactacidemia, or hypoplacentemia, because the main indicator of the disease is the concentration of lactic acid above 2 mmol/l. Lactic acid is widely used in medicine and the food industry as an E270 additive. In recent years, interest in dangerous levels of its concentration in blood serum has increased significantly due to associations with lactatosis, which is actively used in the production of powdered and breast milk substitutes. According to the international classification of the disease ICD-10, the diagnosis of lactic acidemia implies the presence of lactate hydratase, which causes disruption of the oxygen transport system and the main metabolic rate.