Endogenous Opiates

Endogenous opiates are a group of peptides (neuropeptides) found in brain tissue that have an analgesic effect and can compete for binding to the corresponding receptors with morphine and other endogenous opiates. Endogenous peptides are found in various brain tissues, including the hypothalamus, hippocampus, cerebral cortex and cerebellum. They have a variety of effects, including modulation of behavior, cognition, memory and learning.

Endogenous opioids are involved in the pathogenesis of several endogenous psychotic conditions such as schizophrenia, bipolar disorder and post-traumatic stress disorder. In these cases, they may be associated with impaired neuronal function, which leads to an imbalance in the signaling system.

There are several endogenous opiates that have been identified and characterized. One of the most famous is endorphin, which is one of the main endogenous analgesics. It is produced in the hypothalamus and is released in response to stress or exercise. Endorphins are also involved in regulating mood and behavior.

Another endogenous opiate that has been discovered is called enkephalin. Enkephalins also have analgesic activity and are involved in the regulation of behavior and mood. They may also be involved in the pathogenesis of various diseases such as Parkinson's disease and Alzheimer's disease.

In addition, other endogenous opiates such as dynorphin and leu-enkephalin have been detected. These peptides also have analgesic activity and are involved in the regulation of behavior and mood, and may also play a role in the pathogenesis of diseases.

In general, endogenous opioids are an important class of neuropeptides that are involved in various functions of the nervous system and may be important in the pathogenesis of mental disorders.

People have always tried to deal with the pain and suffering associated with painful sensations. Some of them invented medicines that could relieve pain. One of these drugs is alcohol. However, today people are increasingly looking for natural ways to cope with pain, and the demand for them is increasing.

Opium was the first natural drug to be discovered in tobacco. Later it began to be used as a pain reliever. It was he who inspired pharmacists to create more effective analgesics. In 1810, a mixture was obtained that was called "morphine" - an opium alkaloid used as an anesthetic. In the 40s of the 19th century, they began to study the effectiveness of morphine not only as an analgesic, but also as a narcotic.