Lanoxin

Lanoxin: description of the drug

Lanoxin is a cardiotonic drug that is used to treat various heart diseases. The active substance of the drug is digoxin, which is a cardiac glycoside.

The manufacturer of Lanoxin is Glaxo Wellcome, which is located in the UK. The drug is available in the form of tablets of 0.25 mg.

Indications for use

Lanoxin is used to treat the following conditions:

1. Congestive circulatory failure (without hemodynamically significant obstruction of the cardiac outflow tract)
2. Atrial tachyarrhythmia
3. Supraventricular paroxysmal tachycardia
4. Atrial flutter

Contraindications

Lanoxin is contraindicated in case of glycoside intoxication.

Side effects

The following side effects may occur when using Lanoxin:

1. Nausea
2. Vomit
3. Anorexia
4. Bradycardia
5. Ventricular extrasystole
6. AV block
7. Headache
8. Dizziness
9. Color vision impairment
10. Decreased visual acuity
11. Scotomas
12. Macro- and microopsia
13. With long-term use - gynecomastia

Interaction with other drugs

When Lanoxin is used simultaneously with certain other drugs, interactions may occur that may affect the effectiveness and safety of treatment. For example:

1. Adrenomimetics may increase the likelihood of developing arrhythmia
2. Antiarrhythmic and anticholinesterase drugs may cause bradycardia
3. Glucocorticoids, saluretics and other drugs that promote potassium loss can lead to glycoside intoxication
4. Calcium supplements can cause glycoside intoxication
5. Aminazine can reduce the cardiotonic effect of Lanoxin
6. Laxatives, antacids and other products containing aluminum, bismuth or magnesium may reduce the absorption of Lanoxin
7. Rifampicin and sulfasalazine may speed up the metabolism of Lanoxin

Overdose

An overdose of Lanoxin may cause the following symptoms: arrhythmia, AV block, vomiting, nausea. Treatment includes the use of potassium preparations, unithiol and ethylenediaminetetraacetate.

special instructions

When combining Lanoxin with diuretics and sympathomimetics, you must be careful. The combined use of Lanoxin should be avoided, as this can lead to the development of glycoside intoxication.

You should also be careful when using Lanoxin in patients with obesity, electrolyte imbalance, hypokalemia, hypomagnesemia, hypoxia, hypothyroidism and other conditions that may affect the metabolism and effect of the drug.

When treating with Lanoxin, it is necessary to regularly monitor the level of potassium in the blood and the electrocardiogram.

Finally, it should be noted that Lanoxin is a prescription drug that should only be used as prescribed by a doctor.