Leukopenin

Leukopene or leucopene is a glycoside contained in an extract from the young roots of the plant Leucojum aestivum L., of the Amaryllidaceae family. It got its name from the number of blood leukocytes present in it, which decrease under its influence. It was first isolated and described by the German chemist Kunz in 1867.

Chemical composition

Contains an amorphous pigment consisting of glucosuridine, estrin and small amounts of other furan derivatives. In addition, lycopene contains the substance fehentlin and carotenes. The ash contains about 7% CaCO3, calcium hydroxide.

Distribution in nature

Found only in plants of the amaryllis family - Allium, poisonous. According to data from various sources, wild Allium is found in Europe, the Caucasus, North America, and Asia Minor. Leaves (usually roots and bulbs) of Allium are used for medicinal purposes.

The essence of the effect on the human body Leukopine (Leucopoeinum, Leucopen, Leukopoinien, Luecopoein) belongs to the group of bitters and has a weak laxative effect. When used in higher doses, it has a laxative, antiallergic effect. Included in the group of essential foods: it causes hyperemia of the external mucous membranes and has a laxative effect.

Leucoplin is a substance found in various fruits and vegetables and is known for its anti-inflammatory properties. It is a natural inhibitor of cyclooxygenase-2 (COX-2), an enzyme that promotes the production of prostaglandins, the main mediators of inflammation. Leucopline also has an antioxidant effect, strengthens the immune system and helps reduce blood cholesterol levels.

There are many methods for extracting leucopline from the plant, but the most effective methods are extraction from fruits or vegetables. Extraction can be carried out with hot water, acids, alkalis, and also by combining several extraction methods. These processes can change the original properties of leukoplain, so it is necessary to analyze it to determine its concentration and activity.

The mechanism of action of leukopaline is to prevent leukocyte aggregation, which is a key stage in the development of inflammation. In addition, leukoppine helps normalize the activity of T-cells of the immune system and prevent fibrosis. Due to its anti-inflammatory effect, leukoppine is used as an antirheumatic agent and to combat malignant neoplasms.

In addition, leukopilin increases the concentration of growth factors secreted by the endothelium, such as VEGF, TGFA, HIF-1 and others. This promotes tissue regeneration and reduces inflammation by stimulating endogenous processes aimed at tissue repair. Unfortunately, there is currently no scientific data on the side effects of using leucopllin extract. However, some people may experience side effects from consuming it, such as an allergic reaction to its components. Therefore, before using leukoppine, you need to test for allergies.