Levemir Penfill: intermediate-acting insulin
Levemir Penfill is a drug intended for the treatment of diabetes mellitus. It belongs to the group of intermediate-acting insulins and is manufactured by Novo Nordisk A/S in Denmark. The international name of the drug is insulin detemir, and it can also be known under the synonym Levemir FlexPen.
The dosage form of Levemir Penfill is a solution for subcutaneous injection 100 U/ml, and its active substance is insulin detemir. The drug is presented in the form of injection foam syringes, which makes it convenient for use by patients.
Indications for use of Levemir Penfill are diabetes mellitus. The drug can be used as monotherapy or in combination with other drugs to treat this disease.
However, the drug also has contraindications for use. These include increased individual sensitivity to insulin detemir or any of the components of the drug. It is also not recommended to use Levemir Penfill in children under 6 years of age, as clinical studies have not been conducted in children under 6 years of age.
Side effects may occur when using Levemir Penfill. They are most often associated with the dose-dependent pharmacological effect of insulin and can manifest as hypoglycemia. This side effect can occur when the dose of the drug is administered too high relative to the body's need for insulin. Other adverse reactions may be associated with the effect on carbohydrate metabolism, at the sites of drug administration, as well as on the sensory organs, nervous and cardiovascular systems.
The interactions of Levemir Penfill with other drugs have not been well studied, but protein binding studies indicate that there are no clinically significant interactions between insulin detemir and fatty acids or other drugs.
Thus, Levemir Penfill is an effective drug for the treatment of diabetes mellitus, which can be used as monotherapy or in combination with other drugs. However, before using the drug, you should familiarize yourself with its contraindications and possible side effects, and also consult your doctor.