Lipoprotein Test

Lipoprotein assays have become widespread methods for studying lipid metabolism associated with many genetic and disease-related conditions. Particularly important is the study of lipoprotein metabolism in patients suffering from dyslipoproteinemia, type III hyperlipidemia and coronary heart disease, as well as for the diagnosis of hyperglyceridemia, atherogenic dyslipidemia and hypercholesterolemia. The lipoprotein test (LPT) belongs to a group of quick and inexpensive tests that allow you to quickly diagnose disorders of metabolism and metabolism of blood plasma lipoproteins. Lipoproteins are complex compounds of proteins and fats; they transport nutrients between cells and contribute to the saturation of tissues with oxygen. Quantitative determination of lipoprotein levels in the blood is carried out using the LPT method. Blood taken from the patient is treated with physicochemical reagents, then spectrophotometric study is carried out. After the test, the results are displayed on the device screen and processed by a computer. Normally, most plasma lipoproteins have a fairly stable form. Among them are very low density lipoproteins. This is due to the fact that free cholesterol directly passes from the perivascular space into subcellular structures, bypassing lipoprotein lipase. Therefore, the formation of aggregated forms of cholesterol - lipoprotein is considered unlikely. As a result, a stable micelle is formed, where cholesterol and protein are synthesized, ensuring its stable state. If the functionality of the lipoprotein synthesizing complex begins to work intermittently, then the content of non-esterified cholesterol in the plasma increases. Thus, dysfunction of liver cells, their enzymes and transport proteins negatively affects LDL. The same consequence is fraught with the presence of autoimmune antibodies, high levels of free fatty acids and a decrease in the level of high triglycerides in the blood, insulin resistance, chronic inflammation and low levels of vitamin D.

Lipoprotein test (LPS) is one of the many groups of biochemical methods that is used to determine the level of lipoproteins in serum and other biological fluids of the body. It is an inexpensive and informative way to diagnose a wide variety of lipid metabolism disorders, such as hyperlipidemia, disturbances in the ratio of lipid fractions and inflammatory processes, as well as heart and vascular diseases.

The method is based on the dependence