Lovastatin

Lovastatin: an effective drug for lowering cholesterol levels

Lovastatin is one of the leading drugs in the group of lipid-lowering drugs known as HMG-CoA reductase inhibitors. It is widely used to treat hypercholesterolemia and atherosclerosis. Lovastatin helps lower bad cholesterol levels in the body, which improves overall health and reduces the risk of developing cardiovascular disease.

Lovastatin is manufactured by Medokemi Ltd in Cyprus and is available in the form of 20 mg tablets. The active substance of the drug is lovastatin.

Lovastatin has several synonyms, including Cardiostatin, Lovasterol, Mevacor, Medostatin, Rovacor and Choletar. This drug has various pharmacological properties that make it effective in the treatment of hypercholesterolemia and related conditions.

The main indications for the use of lovastatin are hypercholesterolemia and atherosclerosis. It is effective in cases of primary hypercholesterolemia types IIa and IIb, when diet therapy does not provide sufficient effect. Lovastatin can also be used for combined hypertriglyceridemia (hyperlipoproteinemia type IIb).

However, there are some contraindications to the use of lovastatin. It is not recommended in case of hypersensitivity to the drug, impaired renal function, severe liver failure, persistent increase in the level of transaminases in the blood plasma, pregnancy, lactation and childhood.

Side effects may occur when using lovastatin. This may include liver dysfunction, increased transaminase levels, dizziness, mental disorders, convulsions, dyspepsia, flatulence, nausea, vomiting, heartburn, dry mouth, taste disturbances, anorexia, constipation, diarrhea, hepatitis, headaches, muscle pain, myopathy , rhabdomyolysis, general weakness, chest pain, arthralgia, insomnia, paresthesia, optic atrophy, cataract development and allergic reactions.

It is important to pay attention to the interaction of lovastatin with other drugs. Cyclosporine may increase plasma levels of active metabolites of lovastatin. Cholestyramine and bile acid binders may reduce the absorption of lovastatin. In addition, lovastatin may increase the risk of myopathy and rhabdomyolysis when used concomitantly with certain other drugs, such as fibrates, cyclosporine, macrolide antibiotics and protease inhibitors.

The dosage of lovastatin should be determined by the physician depending on the individual characteristics of the patient and the characteristics of his disease. It is usually recommended to start with a dose of 20 mg once daily in the evening, taking the drug during or after meals. The dose can be adjusted depending on the effectiveness of treatment and tolerability of the drug.

Lovastatin is an effective drug for lowering cholesterol levels and treating hypercholesterolemia. However, before you start using it, you must consult your doctor and strictly follow his recommendations. It is important to remember that self-medication can be dangerous, and only a qualified healthcare professional can determine the appropriate dosage and regimen of medication.