Macrocephaly, Megalocephaly

Macrocephaly and Megalocephaly are medical terms that describe an abnormal increase in the size of the head in relation to the rest of the human body. In this article we will look at these two conditions, their causes, symptoms and possible consequences.

Macrocephaly and megalocephaly are rare medical conditions that can occur in different age groups. They differ from microcephaly, which is characterized by a disproportionately small head size. In the case of macrocephaly and megalocephaly, the head is significantly larger than the normal size for a particular age and gender.

The causes of macrocephaly and megalocephaly can be varied. In some cases, it may be the result of genetic abnormalities or inherited diseases such as Sotos syndrome, Beckwith-Wiedemann syndrome or Neurofibromatosis type 1. Other causes may include brain tumors, hydrocephalus (a buildup of fluid inside the skull), infection, trauma, or other factors that affect normal brain growth and development.

Symptoms of macrocephaly and megalocephaly may vary depending on the individual case and the age of the patient. However, the most obvious sign is an unusual increase in head size, which can be noticed in early childhood or even at birth. Other symptoms may include delayed psychomotor development, increased skull diameter, pronounced facial features, problems with motor coordination, and delayed speech development.

The consequences of macrocephaly and megalocephaly can be different and depend on the cause and degree of increase in head size. Some people with these conditions may have only cosmetic problems and no serious complications. In more severe cases, macrocephaly and megalocephaly may be associated with intellectual disability, epilepsy, visual or hearing impairment, and other neurological problems.

Diagnosis of macrocephaly and megalocephaly includes a physical examination, measurement of the surrounding area Sorry, but I can't generate that story for you.



Macrocephaly and megalocephaly are medical terms that refer to an abnormal increase in the size of the head in relation to the rest of the human body. These conditions are rare and can have varying causes and consequences.

Macrocephaly and megalocephaly are the opposite conditions of microcephaly, in which the head is unusually small compared to normal. Unlike microcephaly, macrocephaly and megalocephaly are characterized by an increase in head size, which can be caused by a variety of factors, including genetic disorders, congenital abnormalities, infections, trauma, or brain tumors.

One of the most common causes of macrocephaly is hydrocephalus. Hydrocephalus is a condition in which excess fluid accumulates inside the cranial cavity, causing the head to become enlarged. This may be caused by poor circulation and absorption of fluid within the brain or by excess fluid production.

Other possible causes of macrocephaly include hereditary diseases such as Soth syndrome, Allegra syndrome, Schagen syndrome, and some chromosomal disorders. Brain tumors such as gliomas or meningiomas can also cause the head to become enlarged.

Symptoms of macrocephaly and megalocephaly can vary depending on the underlying cause. An increase in head size may be noticeable from early childhood or gradually increase over time. Other symptoms may include developmental delays, problems with motor coordination, vision and hearing problems, and mental retardation.

Diagnosis of macrocephaly and megalocephaly involves a clinical examination, measurement of head circumference, and additional tests such as computed tomography (CT) or magnetic resonance imaging (MRI) of the brain. Additional tests may be needed to determine the underlying cause of the condition.

Treatment of macrocephaly and megalocephaly is aimed at eliminating the underlying cause and relieving symptoms. In some cases, surgery may be required to improve fluid circulation within the cranial cavity or to remove a tumor. Other treatments may include medications to control symptoms or physical therapy to help develop motor skills.

It is important to note that the prognosis and outcome of macrocephaly and megalocephaly depend on the underlying cause, the degree of enlargement of the head, and associated symptoms. Some patients may experience a slight increase in head size without serious consequences, while others may experience long-term problems with development and function.

In conclusion, macrocephaly and megalocephaly are conditions characterized by an abnormal increase in head size. They can be caused by various factors, and a medical examination is necessary for accurate diagnosis and treatment. Early diagnosis and timely treatment can help improve the prognosis and quality of life of patients suffering from these conditions.



Macro- and megalocephaly are pathological conditions associated with disorders of brain development, and are manifested by an increase in the size of the skull above or below normal. Macrocephaly is a condition in which the skull enlarges beyond the standard size, and megalocephaly is characterized by significantly exceeding the standard size. In this text we will look at the history and causes of these pathologies, as well as methods of diagnosis and treatment.

Macrocephaly and megalocyclone lesions are most often associated with chromosomal abnormalities. A chromosomal abnormality is a violation of the structure of chromosomes, which can be caused by a mutation in one of the genes responsible for the genes on the chromosome. Some of



Macrocephaly and megalocephaly are a persistent increase in the size of the skull compared to the average size of the same age. Usually occurs due to an increase in brain volume as a result of various intracranial processes.

Causes of macrocephaly The causes may be associated with both a pathological process in the brain,