Mastocyte

Mast cells are cells of the immune system that are found in human blood and play an important role in protecting the body from infections and other diseases. They are part of the leukocyte system and perform the function of phagocytosis - the absorption and destruction of bacteria and other foreign substances.

Mast cells are oval in shape and covered with a thin membrane, which provides them with protection from external influences. Inside mast cells is a nucleus containing genetic information and organelles necessary for their functioning.

One of the main functions of mast cells is the production of histamine and other inflammatory mediators. When mast cells detect foreign substances in the body, they begin to release these mediators, which cause vasodilation, increased body temperature and other symptoms indicating the presence of infection or other diseases.

In addition, mast cells are involved in regulating the immune response and can interact with other cells of the immune system, such as T lymphocytes. They also play a role in the development of allergic reactions and autoimmune diseases.

However, despite their importance to human health, mast cells can cause problems if their numbers in the blood become too high or too low. This can lead to various diseases such as mastocytosis, a condition in which mast cells begin to multiply uncontrollably.

In general, mast cells play an important role in the human immune system and are key components of the body's defense against infections. However, their imbalance can lead to serious illnesses, so it is important to monitor their quantity and functioning.



Mastocytosis is a disorder in which too many mast cells are produced in the bone marrow. With the development of pathology, the amount of these elements can reach 90% of the total cell mass.

Clinical picture of the disease. Such a disease is always accompanied by symptoms such as: - nodules on the body or scalp, which can be dense formations ranging in size from 0.5 to 3 cm; - increased body temperature; - skin pigmentation in certain areas, looks like “dried out” skin with light spots; - allergic manifestations, such as