Medicinal substance Non-steroidal Anti-inflammatory (Nsaid, Nonsleroidal Anti-Inflammatory Drug)

Nonsteroidal Anti-Inflammatory Drug (Nsaid, Nonsleroidal Anti-Inflammatory Drug) is a representative of a large group of medicinal substances that are used for pain relief (especially for rheumatism). These drugs inhibit enzymes responsible for the synthesis of prostaglandins, which are important mediators of inflammation. These medications include: aspirin, azapropazone, diflunisal, ibuprofen, ketoprofen, and naproxen. Side effects from taking them are the development of gastric bleeding and the formation of stomach and duodenal ulcers.

**Introduction** Pain management is a very important medical problem that causes concern for all people who are sick. This is due to the fact that any type of pain brings great discomfort to our lives, reduces performance and worsens the quality of life. Therefore, special importance is given to a group of medications that can reduce or eliminate pain in humans. **Main part** Nonsteroidal anti-inflammatory drugs (NSAIDs) are a large group of drugs that are used for pain relief and have anti-inflammatory effects. They belong to universal medicines and are prescribed both for stomach diseases and for inflammatory changes in the musculoskeletal system. Most often, these medications act throughout the body. In simple terms, drugs suppress inflammatory processes. The prescription of such medications occurs only after consultation with the attending physician.

Representatives of the NSAID group have a non-steroidal structure of the main substance, which can have a blocking effect on the synthesis of inflammatory mediators. These medications have a significant effect on temperature, as well as on blood pressure levels, namely by reducing it. This advantage also has a disadvantage. In people with low blood pressure, NSAIDs are contraindicated. It is also not recommended to take these medications if you have a stomach ulcer, especially when the ulcer or erosion bleeds. Once in the body, the medication affects the diseased organ and blocks blood clotting. Medicines: * Aspirin. For the treatment of patients using blood thinning medications. * Naproxen - helps eliminate the effects of inflammation. * Indomethacin - has a strong anti-inflammatory effect. **Conclusion**

Medicinal substances: Anti-Anti-pain Non-steroidal

Nonsteroidal anti-inflammatory drugs (NSAIDs) are among the most popular and widely used medications in the world. These medications are used to reduce pain and relieve inflammation. They work by blocking the enzyme that is responsible for