Megalocyte

Megalocytes are red blood cells that are large in size and contain large amounts of hemoglobin. They are formed in the bone marrow and then enter the blood. Megalocytes can be caused by various reasons such as anemia, infection, poisoning, trauma, etc.

Megalocytes are of great importance to the body as they help transport oxygen to tissues and organs. However, if the number of megalocytes in the blood becomes too high, it can lead to increased blood viscosity and difficulty in blood circulation.

Various methods are used to treat megalocytosis, such as blood transfusions, medications, and lifestyle changes. For example, to reduce the number of megalocytes, you can increase your intake of fluids and foods containing iron. It is also important to avoid smoking and drinking alcohol, as these substances can worsen your health.

Overall, megalocytes are an important part of the blood system, but too many of them can lead to serious problems. Therefore, it is important to monitor your health and consult a doctor if you experience any symptoms related to megalocytes.



Megalocytes (from ancient Greek μέγας “big”, Latin cellula “cell”) are very large anucleate red blood cells that are formed in the bone marrow in response to infectious diseases (borreliosis). Their number can be increased in many diseases. The number of megalocytes in the blood can reach several percent.

Megalocytes are formed in patients, since the presence of a large number of immune cells-macrophages in the peripheral blood indicates the presence of an infectious disease in the body. Some varieties of borreliosis can lead to the formation of megalocytic erythroblasts, with a higher rate of maturation, which leads to increased activity of the circulatory process and the development of potentially dangerous arrhythmias and thromboembolic events. Detection of megalocytosis (both single and multiple and for any duration of the disease) requires an appropriate examination for the timely detection of heart failure and cardiomegaly. In case of detectable cardiomegaly, hemodialysis may be prescribed. To test for Borrelia, ELISA or PCR methods are used.