Leukemic meningitis, also known as meningeal leukemia, meningoleukemia or leukemic meningopathy, is a rare complication of leukemia, a cancer that affects the body's hematopoietic system. Leukemic meningitis is an inflammatory disease of the brain and spinal cord caused by the infiltration of leukocytes into the meninges (the lining of the brain and spinal cord).
The appearance of leukemic meningitis is associated with the presence of leukemic cells in the cerebrospinal fluid (CSF). This may occur due to the spread of leukemic cells through the blood to the meninges or due to the direct spread of leukemic cells from the brain.
Symptoms of leukemic meningitis include headache, nausea, vomiting, burning sensation in the spinal column, convulsions, changes in consciousness, dizziness, headaches, swollen cervical lymph nodes and neurological disorders. These symptoms may appear gradually or suddenly.
To diagnose leukemic meningitis, a cerebrospinal fluid puncture is performed, during which a small volume of cerebrospinal fluid is removed and examined for the presence of leukemic cells. A CT scan of the brain or magnetic resonance imaging may also be prescribed.
Treatment for leukemic meningitis includes chemotherapy and radiation therapy, as well as the use of corticosteroids to reduce inflammation. In some cases, surgery may be required.
In general, leukemic meningitis is a serious complication of leukemia and requires immediate treatment. Early diagnosis and treatment can reduce the risk of complications and increase the chances of recovery. If you suspect leukemic meningitis, you should consult a doctor.