Metoclopramide-Fpo

Metoclopramide-FPO

Country of origin - Russia
Pharm-Group - Antiemetics

Manufacturers - Obolensk Pharmaceutical Enterprise (Russia)
International name - Metoclopramide
Synonyms - Apo-Metoclop, Vero-Metoclopramide, Gastrosil, Dibertil, Melomid, Metamol, Metoclopramide, Metoclopramide-Acri, Metpamid, Perinorm, Raglan, Ceruglian, Cerucal, Cerulan
Dosage forms - tablets 10 mg
Composition - Active substance - metoclopramide.

Indications for use - Nausea, vomiting, functional digestive disorders, reflux esophagitis, atony and hypotension of the stomach and duodenum; preparation for diagnostic studies of the gastrointestinal tract.

Contraindications - Hypersensitivity, glaucoma, pheochromocytoma, epilepsy, Parkinson's disease and other extrapyramidal disorders, pregnancy (first trimester), breastfeeding (breastfeeding should be stopped during treatment).

Side effects - Dry mouth, constipation or diarrhea, drowsiness, depression, extrapyramidal disorders (convulsive twitching of the facial muscles, impaired movement of the eyeballs, protruding tongue), edema, galactorrhea, hyperprolactinemia, menstrual irregularities, hyperemia of the nasal mucosa, skin rashes.

Interaction - The effect of the drug can be weakened by anticholinesterase drugs. Antipsychotics increase (mutually) the likelihood of developing extrapyramidal disorders. Strengthens the sedative effect of sleeping pills and alcohol. Slows down the absorption of digoxin, accelerates the absorption of paracetamol, tetracycline, levodopa, ethanol.

Overdose - Symptoms: hypersomnia, disorientation, extrapyramidal disorders. Treatment: usually go away on their own within 24 hours after discontinuation of the drug; if necessary, prescribe anticholinergic and antiparkinsonian drugs.

Special instructions - The possibility of decreased concentration and increased reaction time during treatment should be taken into account (it is better to avoid driving a car and working with potentially dangerous equipment). During the treatment period, alcohol consumption is not recommended. The injection solution must not be mixed with alkaline infusion solutions.

Literature - Encyclopedia of Medicines 2004.