Metronidazole Benzoate

Metronidazole benzoate

Country of origin: India
Pharm-Group: Drugs for the treatment of trichomoniasis, amoebiasis and other protozoal infections

Manufacturers: Unique Pharmaceutical Laboratories (India)
International name: Metronidazole
Synonyms: Aquametro, Apo-Metronidazole, Arilin, Gen-Zolerol, Deflamon, Zoacid, Camezol, Klion, Medazol, Metrovit, Metrogyl, Metroxan, Metrolacare, Metronidazole, Metronidazole IV Brown, Metronidazole Qualimed, Metronidazole Nycomed, Metronidazole-AKOS, Metronidazole-Ros
Dosage forms: substance
Ingredients: Active substance - metronidazole
Indications for use: Amebiasis, trichomoniasis, giardiasis, giardiasis, intra-abdominal infections (peritonitis, abscess), anaerobic infections of bones and joints, skin and soft tissues, female genital organs (endometritis, tubo-ovarian abscess), central nervous system (meningitis, brain abscess), lower respiratory tract (pneumonia, empyema, lung abscess), endocarditis, pseudomembranous colitis, eradication of Helicobacter pylori, chronic alcoholism, prevention of postoperative anaerobic infection. For external and local use: rosacea and vulgar acne, bacterial vaginosis, long-term non-healing wounds, trophic ulcers.
Contraindications: Hypersensitivity (including to other nitroimidazole derivatives), pregnancy, lactation, children (excluding cases of amebiasis).
Side effects: Headache, dizziness, syncope, ataxia, disturbances of consciousness, epileptic seizures, neutropenia (leukopenia), nausea, vomiting, abdominal pain, diarrhea, unpleasant metallic taste, erythematous rashes, skin itching, dark urine discoloration, allergic reactions, thrombophlebitis (after intravenous administration).
Interaction: Enhances the effects of indirect anticoagulants and lithium salts. Phenytoin and phenobarbital reduce the effect (due to activation of the liver microsomal system and accelerate metabolism and excretion), and cimetidine increases (inhibits the enzymatic systems of the liver and, as a result, slows down biotransformation). Incompatible with alcohol (when taken together, an Antabuse-like syndrome develops).
Overdose: Symptoms: nausea, vomiting, ataxia, in severe cases - peripheral neuropathy and epileptic seizures. Treatment: symptomatic; There are no specific antidotes.
Special instructions: When treating with metronidazole, excessive development of fungal flora of the vagina (candidiasis) is sometimes observed, which requires the prescription of antifungal drugs.
Literature: Encyclopedia of Medicines 2006. Directory of medicines M.D. Mashkovsky 14th edition 2000