Mice Encephalomyelitis Virus

Mouse encephalomyelitis virus (syn. Theiler virus) is a virus from the family Togaviridae, genus Alphavirus. It is an RNA virus that causes encephalomyelitis in mice. The virus is carried by mosquitoes and can infect a variety of rodents, including mice, rats and squirrels.

In mice, the virus causes acute inflammation of the brain and spinal cord, resulting in paralysis of the limbs, unsteady gait and other neurological symptoms. The incubation period is 3-7 days. Mortality among mice can reach 90-100%.

This virus poses a danger to laboratory animals and can cause outbreaks in mouse colonies used for scientific research. Therefore, it is important to monitor colonies and take measures to prevent the spread of infection.

Thus, the mouse encephalomyelitis virus is a dangerous neurotropic virus that can cause severe damage to the nervous system and death of laboratory rodents.



Murine encephalomyelitis virus, also known as Theiler's virus, is a small RNA virus of the Picornaviridae family. This virus was first isolated from the brains of mice in 1930, and since then it has become widespread in the rodent world. Murine encephalomyelitis virus can cause various forms of disease, including encephalitis, meningitis and paralysis.

Symptoms of the disease may vary depending on the form of the disease and its severity. Typically, the first symptoms appear 5-7 days after infection and may include fever, loss of appetite, weakness and depression. In more severe cases, seizures, paralysis and loss of coordination may occur.

Murine encephalomyelitis virus is spread through contact with infected rodents, and can be transmitted through blood and other body fluids. Most infected rodents do not show symptoms of the disease, but they can be a source of infection for other animals and humans.

A vaccine against the murine encephalomyelitis virus has been developed and is successfully used to protect laboratory animals from infection. However, there are currently no effective prevention methods to protect pets and people from this virus. Therefore, people working with rodents are advised to take precautions, including the use of protective equipment and proper handling and disposal of waste.

Overall, the murine encephalomyelitis virus is a serious threat to animal and human health, and requires further research to develop effective methods of prevention and treatment.