Myofibrillar Disc

Myofibrillar disc

Myofibrillar disc is the general name for isotropic and anisotropic discs of striated muscle fiber.

Isotropic discs consist mainly of the protein actinin and are located between individual sarcomeres of myofibrils. They ensure the contractility of the muscle fiber, as they allow the sarcomeres to interact with each other and contract synchronously.

Anisotropic disks are located in the middle of the sarcomere and consist of the proteins titin, desmin and others. They provide attachment of thick myofilaments to the Z-line of the sarcomere and play an important role in transmitting tension during muscle contraction.

Thus, myofibrillar discs are extremely important for the normal functioning of skeletal muscles, since they determine their contractile properties. Disturbances in the structure or composition of these discs can lead to various myopathies.

Introduction

Myofibrillar disc is the general name for isotropic (elongated or round) and anisotropic (striated) discs that are located in the body of striated muscle fibers. The discs are located near the nuclei and give the muscles their characteristic appearance. However, despite the common terminology