Marrow Bone Blue

Marrow bone blue (MCB) is a medical term that refers to the microscopic appearance of bone marrow seen in certain blood disorders. The most common disease associated with MCB is pernicious anemia.

Pernicious or glandular anemia is

Bone marrow blue (or pernicious bone marrow picture) is a microscopic technique that examines the bone marrow, which shows blue cells called promegaloblastic cells. This microscopic procedure may be performed on a patient to diagnose pernicious disease, a disease that causes vitamin B12 and folic acid deficiency.

When examining bone marrow, the doctor needs to take several sections of bone tissue to find out what cells are in it. If a predominance of cyanophilic promegaloblactic and basophic