Neurodermatitis diffuse is an inflammation of the skin without a specific onset of the disease, but chronic. This is one of the types of neurodermatitis, which is characterized by a long course and itching of varying degrees of intensity. The number of cases of this type is more than 5% of the population. Most often it is localized on the skin of the torso, head, neck, less often on the palms, soles and legs. The disease can appear at any age, but most often occurs in children under five years of age and adults. At an early stage, quite often the patient is diagnosed with atopic dermatitis. Diffuse neurodermatitis causes prolonged psychological discomfort and disorientation of the patient. Dermomania is often accompanied by sleep disturbances, irritability, anxiety, and mood swings. The patient may experience obsessive ideas, anxiety, even panic attacks. They are permanent and continuous. The characteristic features of the disease depend on the general condition of the body and the individual characteristics of the person. Symptoms are divided into different types, for example, mild itching can be combined with severe discomfort when urinating. As a result, a person may stop taking care of himself. The manifestation of diffuse neurodertitis is possible in any part of the body, so it is extremely important to diagnose the disease in a timely manner and prescribe adequate treatment.