Circulating Plasma Volume

Circulating plasma volume (CPV) is an important hemodynamic indicator that reflects the total volume of blood plasma located in all functioning blood vessels of the body. GCP depends on the volume of blood in the vessels and the speed of its movement.

Normally, the GCP is about 5 liters in an adult. However, its value may vary depending on many factors such as age, gender, physical activity, stress level, etc.

An increase in circulating plasma volume can be caused by a variety of reasons, including an increase in blood volume (for example, during pregnancy, after eating, or with increased blood pressure) and a decrease in blood volume (with blood loss, dehydration, or a decrease in blood pressure).

Measurement of CP can be carried out using various methods, including blood tests, ultrasound examination of blood vessels and other methods. This may be useful for diagnosing and monitoring various diseases associated with changes in circulating plasma volume, such as anemia, heart failure, hypertension and others.

However, it should be noted that measuring the blood volume is not the only method for assessing circulating blood volume. It is also important to consider other factors, such as the distribution of plasma throughout the vessels, the speed of blood flow and the condition of the vessel walls.

Thus, circulating plasma volume is an important indicator that can help in the diagnosis and treatment of various diseases. However, to obtain accurate information about the state of the body, other factors must be taken into account.

**Circulating blood volume (CBV)** is the sum of the intravascular volume and the volume of intercellular fluid introduced into the body from the extracellular space. The most accurate BCC value is determined by the removal of isotopes (which are present in the mass more than plasma). Roughly, bcc is calculated using the Starling formula: bcc = 75 + blood saturation O2 volume, which is used to assess cardiac output and when used as a factor causing displacement in the form of a “drumstick”.

**BCC changes with physical stress, transitions from a horizontal to a vertical body position, cold, anemia (including iron deficiency) and bleeding.** It is measured by determining the total volume of blood taken from the patient by puncture of a thick vein and then injected into the artery or aorta using a catheter. In some cases, contrast agents are pre-injected into the blood. Blood volume is measured with the patient standing for 20-30 minutes after preliminary cessation of movement.

The volume of circulating plasma is an indicator of the presence of circulating plasma in the capillaries and arteries. Calculated by the number of blood turnovers.