Auberge Isoantigen

Aberger or ABO antigens are an antigen that determines group immunity in humans. It is also called isoantigens of the Auberge system. Sometimes it is also called “A”, which is not entirely correct, since it determines only the blood group without taking into account other factors, but this is the name traditionally used to designate this antigen. The development of this antigen was carried out by the Wasserman company, which studied the nature of infectious hepatitis at the turn of the 19th and 20th centuries. Thanks to the first guesses of A.P. Chekhov, criminologist E. Koenig was the first to use the Auberge system as the main criterion in determining the form of hepatitis. Now the role of this protein has been reduced to use in addition to various types of agglutinins. However, antibodies are still used as tests to determine a person's blood type.

It is worth noting that the Auberge antigen itself is a macroglobulin, but is capable of eluting in the absence of anti-agglutinins, although, as a rule, its presence suppresses most agglutinins. It is a protein that contains amino acids, specific antibodies, and nucleic acids. Found in peripheral blood lymphocytes, where its concentration is ~9 ng/ml. Of the extracellular structures, it is determined only in tissues, and with age, the percentage of isoantigen content