Ophthalmotropism Adenohypophyseal

Adenohypophyseal ophthalmotropism (ophthalmotropismus adenohypophysialis) is the property of hormones of the adenohypophysis (anterior pituitary gland) to have a regulatory effect on the functions of the organ of vision.

The adenohypophysis produces several hormones that affect eye function:

  1. Adrenocorticotropic hormone (ACTH) stimulates the adrenal cortex to produce the hormones cortisol and aldosterone, which are important for the normal functioning of the retina.

  2. Thyroid-stimulating hormone (TSH) regulates the function of the thyroid gland, whose hormones (triiodothyronine and thyroxine) are necessary for the normal development and functioning of the eyes.

  3. Prolactin is involved in the regulation of intraocular pressure.

  4. Somatotropic hormone (GH) affects the growth and regeneration of eye tissue.

Thus, the hormones of the anterior pituitary gland have a multifaceted regulatory effect on the organ of vision, which is called ophthalmotropism of the adenohypophysis. Impaired production of these hormones can lead to the development of various eye diseases.



Ophthalmotropic adenopituitary gland is a rare form of neurooncological tumor, most often arising in the tissues of the midbrain - less often in the hypothalamus and, most rarely, in the surgically unexplored posterior regions. These tumors are more common in men.

The tumor develops during several stages, which consist of several stages, but, as a rule, have a similar pathological process. The tumors can vary in size, color and possibly appearance, from a small dot to a large, spider-like, grayish mass. Depending on the shape of the tumor and its location, vision problems or, conversely, a complete absence of any symptoms may occur.

For example, if the tumor is in the optic nerves, it may put pressure on vision or cause some eye problems, such as difficulty seeing certain things. In other cases, if it grows in brain tissue, the patient may experience dizziness, decreased cognitive function, emotional disturbances, trouble sleeping, or constant fatigue. Sometimes, simply by finding something that looks like a tumor, ophthalmologists can refer the patient for additional diagnostics to determine whether the tumor is associated with ophthalmotropic adenohypophysis.

However, it is important to note that only a portion of patients with ophthalmic