Chromaffin blast tumors are neuroendocrine tumors that arise from the chromaffin cells of the adrenal medulla. The adrenal glands are located on top of the kidneys, and they are involved in regulating stress and metabolic homeostasis. Adrenal diseases, including chromaffin tumors, are a serious medical problem that requires timely diagnosis and treatment. This article will discuss the definition of chromaffins, the causes of chromaffin cell tumor development and its symptoms, diagnostic and treatment methods, and the prognosis for patients.