Osteogenesis

Osteogenesis is the process of formation and development of bones in the human body. This process begins in the embryonic period and continues throughout life.

Osteogenesis occurs in two main zones - the metaphysis and diaphysis. The metaphysis is the area of ​​bone that lies between the epiphysis and diaphysis. The diaphysis is the central part of the bone where growth and development occur.

The process of osteogenesis includes several stages:

1. Cell growth and differentiation. During this stage, cells called osteoblasts begin to multiply and differentiate into osteoblasts, which then begin to form bone tissue.

2. Matrix formation. Osteoblasts produce collagen and other proteins that form the matrix of bone. This matrix is ​​the basis for the formation of new bone.

3. Formation of new bone. Osteoblasts begin to produce new bone cells that form new bone.

4. Calcification. Once new bone is formed, it begins to calcify, making it stronger and more resistant to stress.

5. Bone growth. After osteogenesis is complete, bone continues to grow in length and width, allowing it to adapt to changing loads and environmental conditions.

Disruption of the osteogenesis process can lead to various bone diseases, such as osteoporosis, osteomyelitis, osteosarcoma, etc. However, healthy osteogenesis is necessary for normal growth and development of the body.

Osteogenesis (English osteogenesis from ancient Greek ὀστέον “bone” + γενέσις “generation”; bone growth) is the formation of bone. It is not synonymous with osteogenesis in the meaning of “composition of skeletal bones.” Osteogenesis in this sense is understood as a set of processes that ensure the reproduction of the structure and composition of bone.

Osteogenic tissue is the main working material in the process of bone formation in an adult. In postnatal ontogenesis, bones are formed by the induction of two types of cells: - osteocytes, which are dense cells of various sizes and perform mainly a plastic function and - osteoblasts, which are cells

Osteogenesis or bone formation is the process of growth and formation of bone tissue. It arises from mesenchyme. The development of osteogenesis begins after the birth of a child. First, the human body receives the required amount of matrix substance, thanks to which the active growth of cells begins, on which bone tissue subsequently appears. Over time, this process is accompanied by the establishment of conditions and a balance of chemical components. The rate of osteogenesis is due to the fact that a person must grow. Normal physiology assumes that bone formation occurs evenly over the entire area, and their growth is combined with the constant development of joints.