Osteoid tissue

Tissue Osteogenic

Osteogenic tissue is a type of connective tissue that is formed from mesenchyme and is involved in bone formation. It contains osteoblasts, which are the cells responsible for the formation of bone tissue.

Mesenchyme is a special type of connective tissue from which all organs and tissues of the body are formed. It consists of fibroblasts, mast cells, macrophages, histiocytes and other cells.

During bone development, mesenchymal cells migrate to the future bone site and begin to differentiate into osteoblasts. Osteoblasts divide and form bone tissue, which fills the space between blood vessels.

The process of bone formation is called osteogenesis. It occurs under the control of the hormone calcitonin, which regulates calcium levels in the blood. If there is not enough calcium, osteoblasts begin to produce less bone tissue and the process of osteogenesis slows down.

In addition to osteoblasts, osteogenic tissue contains osteocytes - cells that perform the function of storing calcium and phosphorus. They are also involved in the metabolism between blood and bone.

Osteogenic tissue plays an important role in bone development, as well as in the repair and regeneration of bone tissue after injury or disease.



**Osteogenic tissue** (Latin t. osteogénica, osteogenicus of bone origin) is the name of a tissue whose derivative cells participate in the biogenesis of bone tissue. Osteogenesis is regulated by local vascularization of various parts of the skin and is associated with cell proliferation, histogenesis and differentiation.

The term "osteogen" was first proposed in 1906 by Schiffat to refer to the tissue located in the region of the periosteum, under the perichondrium of the scapula, its connective tissue counterpart around the occipital bone and at the junction of the phalanges of the fingers. Later, an osteogenic temporal bone was described from the region of this perichondrium zone, and reticular tissue with osteogenic cells was described from the overlying fibrous tissue. In 1887, Russell described accumulations of bone cells in reticular skin, fibrous tendons and ligaments, which he called chondromas. By analogy with cells located in cartilage tissue (chondroblasts), such cells, unlike bones, were later called chondroblastoid, cells localized in the fibrous tissue of the perichondrium - osteogenic network, then chondroid, etc.