Papulosis Malignant Atrophic

***Malignant Atrophic papulosis*** is a skin disease caused by the human papillomavirus. It manifests itself in the form of multiple formations on the skin, which can have different shapes and sizes. Papules may be flat or raised, with a dark center and redness around them. They may be painful and cause itching or burning. When they are removed, small wounds are formed that heal in a few days. Papillomaviruses can affect the immune system, causing a decrease in the body's defenses, which leads to relapses of the disease. Papular malignant atrophy is a progressive skin disease accompanied by transformation into malignant neoplasms. The main agent of infection is the papilloma virus. The disease occurs in 3 stages. It is detected when visiting a dermatologist and is also classified by symptomatic signs and palpation of rashes. Treatment begins after determining the stage and identifying the lesion. Examination of patients reveals changes in the structure of cells, the structure of skin cells.

**Malignant papulosis** are localized plaques consisting of small, colorless, sebaceous bodies. The pathogenesis of this disease is not fully understood. Some dermatologists believe that malignant papulase occurs due to an increased content of male sex hormones, others believe that an increase in epithelial cells of the sebaceous glands occurs under the influence of infectious agents - herpes, Epstein-Barr virus, cytomegalovirus, staphylococcus streptococcus and others.

The most common cause of malignant papulosis is skin depigmentation after treatment with a chloride substance. At the same time, the amount of melanin pigment produced in the skin decreases, hence the strange name given to the condition “unfriendly.” Some patients notice a connection with a specific infection. The main pathologies that provoke the occurrence of the disease: * herpes; * EBV, CMV; * infection with strepto- or staphylococci; * syphilis. As an independent pathology, the diagnosis of malignant athyrophic papule is very rare. **The danger lies in the high risk of malignancy over the next 5–7 years.**