Pemphigus (Pemphigus), Pemphigus Vulgaris (Pemphigus Vulgaris)

Pemphigus (Pemphigus) is a rare but serious autoimmune skin disease characterized by the periodic appearance of blisters on the skin and mucous membranes that quickly burst, since the oral cavity and other mucous membranes, as well as the skin, are often exposed to external influences.

Pemphigus vulgaris (Pemphigus Vulgaris) is the most common and severe variant of the disease. In this form, blisters appear on the skin and mucous membranes of the mouth, pharynx, larynx, esophagus, nose, genitals and conjunctiva of the eyes. Bursting blisters leave painful erosions and ulcers that make speech and swallowing difficult.

There are also milder forms of pemphigus - pemphigus foliaceus and vegetans, in which the skin is mainly affected, and the mucous membranes are slightly affected.

The disease requires long-term treatment with immunosuppressants and hormonal drugs. In the absence of adequate treatment, pemphigus vulgaris can be fatal.



Pemphigus (Pemphigus) is a rare but serious autoimmune skin disease characterized by the periodic appearance of blisters on the skin and mucous membranes that quickly burst. This occurs because the oral cavity and other mucous membranes, as well as the skin, are often exposed to external influences. One form of pemphigus is pemphigus vulgaris (Pemphigus Vulgaris), which is considered the most common and severe form of the disease.

Pemphigus is an autoimmune disease, which means that it involves the body's immune system inappropriately responding to its own cells and tissues. In the case of pemphigus, the immune system attacks cells called keratinocytes, which make up the top layer of skin and mucous membranes. This leads to the formation of blisters, which burst, leaving ulcers and ulcers on the surface of the skin and mucous membranes.

Pemphigus vulgaris is the most severe form of pemphigus. It is characterized by the formation of large, easily burst blisters that leave painful ulcers on the skin and mucous membranes. The disease can affect any area of ​​the skin or mucous membrane, but most often the oral cavity, lips, tongue, larynx and external genitalia are affected. Open sores can be very painful and often cause discomfort for the patient.

The cause of pemphigus and pemphigus vulgaris is not completely known, but it is believed that genetic and environmental factors may play a role in the development of the disease. The diagnosis of pemphigus is based on the clinical picture, biopsy and immunological studies.

Treatment of pemphigus and pemphigus vulgaris usually involves the use of systemic immunosuppressive drugs such as corticosteroids and immunomodulators. The goal of treatment is to reduce the activity of the immune system to prevent the formation of new blisters and ulcers. Additionally, topical medications, such as antiseptic solutions and anti-inflammatory creams, may be used to relieve symptoms and speed up the healing of ulcers.

In addition to drug treatment, it is also important to ensure proper care of the skin and mucous membranes. This includes gentle cleansing using gentle cleansers, avoiding irritants and trauma, and maintaining good oral hygiene. Regular consultations with a dermatologist and dentist are also necessary to assess the condition and adjust treatment.

Pemphigus and pemphigus vulgaris are chronic diseases and their treatment may require time and patience. It is important to follow your doctor's instructions and follow recommendations for caring for your skin and mucous membranes. If new symptoms appear or the condition worsens, you should immediately seek medical help.

Although pemphigus and pemphigus vulgaris are serious diseases, modern diagnostic and treatment methods can achieve disease control and improve the quality of life of patients. Seeking medical help early and following your doctor's recommendations are key factors in successfully managing these conditions.

In conclusion, pemphigus and pemphigus vulgaris are rare but serious autoimmune skin diseases. They are characterized by the formation of blisters on the skin and mucous membranes, which quickly burst, causing ulcers and ulcers. Treatment includes systemic medications and proper care of the skin and mucous membranes. Modern diagnostic and treatment methods make it possible to achieve disease control and improve the quality of life of patients.



Pemphigus is considered a complex scarring and usually chronic inflammatory skin disease that affects mainly the lower layers and appears as reddish, blistering-like blisters. This name is primarily used to refer to classic pemphigus vulgaris or herpetic. The latter means “a blister that appears on the skin” and is considered one of the most common types of this disease. Rarer forms caused by other diseases are more often called non-herpetic pemphigus cutaneous vesicular erratic dermatoses, in which many large blisters appear on the skin. This often happens under the influence