Penicillins Semi-synthetic

Semi-synthetic penicillins are drugs that have the properties of penicillin-type antibiotics. They are synthesized by attaching certain chemical groups to 6-aminopenicillanic acid, which is obtained by biological means.

Semi-synthetic penicillins differ from natural ones in that they have an extended spectrum of antimicrobial action and are resistant to penicillinase, an enzyme that destroys natural penicillins.

Semi-synthetic penicillins include drugs such as methicillin, oxacillin, ampicillin, amoxicillin and others. They are active against gram-positive and some gram-negative bacteria.

Widely used in medical practice for the treatment of various infectious diseases.



Semi-synthetic penicillins are one of the most well-known and widely used groups of antibiotics. They were developed after the discovery of penicillin and the creation of antibiotics based on it. Semi-synthetic antibiotics have the same properties as natural penicillium, but contain several additional molecules that improve their activity against bacteria.

Penicillin