Perineural Space

The perineural space (spatium perineurii; synonym perineural vagina) is a narrow space between the endoneurium and the perineurium, filled with relaxed connective tissue and interstitial fluid.

The perineurium is a multilayered membrane surrounding individual nerve fibers and bundles of nerve fibers. The endoneurium is a thin connective tissue sheath covering individual nerve fibers.

Thus, the perineural space is located between these two nerve sheaths. It performs a protective function by absorbing mechanical pressure on the nerve. In addition, it ensures the diffusion of nutrients from blood vessels to nerve fibers. Violation of the integrity of the perineural space can lead to compression of the nerve and the development of neuropathy.

The perineural space is an anatomical structure between the spinal membranes and the dura mater of the brain, filled with loose connective tissue or cerebrospinal fluid.

Etymology

The name comes from the Latin spatium - “interval, interval” and perineurium - “perineural”, the sheath of the nerve.

Anatomy The perineural space occupies the anterior part of the dorsal surface of the spinal cord, as well as the anterior sections of the base and the posterior part of the lateral surfaces of the vertebral bodies. Between the anterior and posterior cranial fossa of each vertebra there are two thin layers of the dura mater - supra- and intrathecal. The posterior ones are firmly fused with the vertebral bodies. The anterior ones are much thinner and can be easily felt in the form of separate leaves. The choroid glomeruli and meninges of the spinal roots are fixed to these edges of the pia mater. Between both layers of the hard shell there is a perineural substance, which forms a continuation of the inner layer of the soft shell. There are no 2-3.5 mm in the paint-scar pool; the main tank is located behind them. At the base of the brain, the space measures 4-6.6 cm, reaching 7.7 cm in the cervical region. On average