Plethora is an increase in the amount of blood in the bloodstream, resulting in a discrepancy between the amount of blood released and a decrease in the volume of the vascular bed. Redness of the skin is also characteristic of plethora - hyperemia. Often, redness is a uniform, moderately pronounced diffuse blush on the cheeks and neck, which does not have any shades or lightening. Sometimes patients with plethora notice redness of the face and neck. With plethora, the face may appear puffy and tired.