Pauling-Cory Spiral

Pauling-Cory spiral: discovery, structure and application

The Pauling-Corey helix is ​​a special type of molecular structure discovered in 1951 by American chemists Linus Pauling and Robert Corey. A spiral consists of turns, each of which contains three atoms connected to each other. This structure is an important element of many biologically active molecules.

Linus Pauling, who received the Nobel Prize in Chemistry in 1954, was famous for his studies of chemical bonding and the structure of molecules. Robert Corey was also known for his work in the field of chemistry, in particular, he developed methods for the synthesis of complex organic compounds.

The Pauling-Cory helix was discovered during research into proteins and nucleic acids. Scientists have noticed that some nucleic acid molecules contain repeating regions that can form a helical structure. This led to the idea that the helix could be a key element in the structure of proteins and other molecules.

The spiral is formed due to a special type of bonds between atoms called hydrogen bonds. Hydrogen bonds occur between the electron clouds of oxygen, nitrogen and hydrogen atoms. These bonds provide stability to the helix and allow it to maintain a certain shape.

The Pauling-Cory spiral has many applications in biological chemistry and medicine. For example, it is used to study the structure of proteins, antibiotics, vitamins and other biologically active molecules. The spiral can also serve as the basis for the creation of new drugs and materials.

In conclusion, the Pauling-Cori spiral is an important discovery in the field of chemistry and biology. She has helped scientists understand the structure of biologically active molecules and open up new opportunities for the development of drugs and materials.



Pauling - Corey helix (English: Pauling - Corey helix, English: PCC helix) is a specific DNA molecule that has a unique and unchanged repeating sequence of nucleotides, forming two subsets. Their structure consists of so-called “traps”, also known as 3’- or 5’-analog helices, which ensure the cohesion of replicons, while the cleavage of a DNA fragment does not lead to the end of replication.

The [[Ohmic effect|effect of DNA oligomerization]], the discovery of which is named after this region