Presubicular Region

The presubicular region (lat. regio presubicularis) is a region of the brain located almost along the entire length of the internal gyrus between the entorhinal cortex and the subiculum of the hippocampal gyrus. The presubicular region differs in its histological structure from adjacent sections and has its own functional characteristics.

The presubicular region contains 6 layers of nerve cells. Unlike the subiculum, pyramidal cells predominate here. The bulk of the nerve fibers in the presubicular region run parallel to the surface of the brain.

Functionally, the presubicular region is closely connected with the subiculum and entorhinal cortex. It plays an important role in the formation of spatial memory and navigation. The presubicular region is involved in the integration of sensory information from the entorhinal cortex and associative information from the hippocampus. Damage to the presubicular region leads to disturbances in orientation in space.

The presubicular region (lat. regio presubicularis) is a structure of the limbic system of the brain, located in the medial part of the temporal lobe.

The name of the region comes from its location in front of the hippocampal base (lat. subiculum). The presubicular region is closely connected to the hippocampus and plays an important role in memory and spatial navigation. It participates in the formation of a cognitive map of the surrounding space and orientation in it.

The presubicular area receives afferent connections from the entorhinal cortex and sends efferent projections to the amygdala, thalamus, and other brain structures. Damage to the presubicular region can lead to memory impairment and spatial disorientation.