Permeability Test

A permeability test is a research method that is used to determine the degree of capillary permeability in the body. It allows you to identify the presence of diseases associated with impaired capillary function, such as diabetes, atherosclerosis and others.

There are several permeability testing methods, but the most common are the Rumpel-Leede-Konchalovsky (RLK) test and the Marsh (M) test. RLK is a more sensitive method that can detect even small changes in capillary permeability.

The RLK test involves applying a dye to human skin, which penetrates through capillaries and is distributed over the surface of the skin. A solution is then applied to the skin, which should penetrate the capillaries, but should not penetrate the skin. If capillary permeability is increased, the dye will penetrate into the solution and a stain will appear on the surface of the skin.

The Marsh test method measures the level of oxygen in the blood. If capillary permeability is increased, oxygen will enter the blood faster and the oxygen level in the blood will be higher.

Both methods are used to diagnose various diseases, such as diabetes, atherosclerosis, rheumatoid arthritis and others. They can also be used to evaluate the effectiveness of treatments for these diseases.

Permeability test: methods for detecting increased permeability and their significance in medicine

The permeability test is a general name for methods that are used to detect increased capillary permeability. Methods depend on what skin or tissue needs to be examined. One of the most popular methods is the peripheral capillary stiffness test (PCS).

The PCS method is performed on the skin in the wrist area. The test result is recorded 15 minutes after the blood cuff is applied; results are also measured after 3 and 7 minutes (to assess the effect of heat and pressure on the result, respectively). If there is no noticeable increase in temperature