Prodromal Period

Prodromal period: what is it and how to recognize it

The prodromal period is the stage of development of the disease that precedes its main clinical manifestations. During this period, the patient may experience some symptoms, but they are often not specific and may be associated with other conditions. At the same time, the prodromal period may be a key point for the diagnosis and treatment of certain diseases.

The prodromal period can last from several hours to several weeks, depending on the type of disease and the individual characteristics of the patient. During this period, the body fights an infection or other cause of illness, and changes occur in the body that may be noticeable, but not always.

Some common symptoms that may appear during the prodrome include:

  1. fatigue
  2. headache
  3. pain in muscles and joints
  4. weakness
  5. elevated body temperature
  6. loss of appetite
  7. nausea and vomiting
  8. insomnia
  9. irritability
  10. mood changes

These symptoms may appear with varying degrees of intensity and frequency, depending on the disease, which is in its early stages. Some illnesses, such as influenza and infectious diseases, may have more specific symptoms, such as cough, nasal congestion, sore throat, etc.

It is important to note that not all diseases go through a prodromal period, and not all symptoms that may appear during this period are specific to a particular disease. Some symptoms may be due to other circumstances such as stress, fatigue, lack of sleep, etc.

However, recognition of the prodromal period can be of great importance for the diagnosis and treatment of diseases. For example, in the case of infectious diseases, early medical attention and treatment can help prevent complications and reduce the risk of transmitting the infection to others.

Additionally, for some diseases, such as schizophrenia and bipolar disorder, the prodrome may be a key point for diagnosis and initiation of treatment. In these cases, early recognition of symptoms and initiation of treatment can help improve the prognosis of the disease and reduce the risk of complications.

In conclusion, the prodromal period is an important point in the development of certain diseases and can have important implications for diagnosis and treatment. Although prodromal symptoms are not always specific to a particular disease, recognizing them and promptly seeking medical attention can help prevent complications and reduce the risk of transmitting the infection to others. In addition, for some diseases, the prodromal period may be a key point for diagnosis and initiation of treatment, which can improve the prognosis of the disease and reduce the risk of complications. Therefore, if you notice any unusual symptoms in yourself or your loved ones, you should not delay contacting your doctor, especially if they continue or get worse over time.



Early prodrome covers two months of a child’s life. This period is characterized by a relatively calm, sometimes to the point of apparent prosperity, course. Only at the end of the second month does the baby experience a shortening of inhalation, which, in the uncomplicated course of typical bronchitis, is noted only in the third week of life.

In the first month of life, suddenly, against the background of complete well-being, sleep is disturbed, the child periodically stops sucking. Over the next three to five days, a persistent shortening of inspiration appears. At first it occurs periodically and lasts 6-15 minutes. Sometimes a cough impulse is added to a yawn. Single attacks of difficulty breathing or rapid breathing and cyanosis occur. A pale grayish skin tone and sweating are often observed. Parents also noticed the child's lethargy and lack of appetite. The temperature remains normal. The increase in clinical symptoms occurs slowly, the time of their appearance is extended over three to four weeks. Sometimes the nervous system is affected. The child experiences severe weakness in the lower extremities, decreased appetite, and inversion of sucking. Temperature and pulse remain normal.

In the second month of the disease, clinical manifestations intensify. The newborn gains little weight and eats poorly. The cough appears every day, except on weekends. Pallor of the skin and limbs occurs. There is a periodic increase in body temperature up to 37.5