Radioautography

*Autography* can be called one of the most amazing research methods that allows you to look into the secrets of DNA structure. There is no other research technology in the world that makes it possible to reconstruct protein structures at the molecular level in real time, observing dynamic processes such as conformational changes, bimolecular interactions and the occurrence of biological reactions. However, despite its high potential, the widespread availability of this method is still very limited.

Perhaps the only recognized *autradiography* method is diffraction autoradiography (DRRG). DXR is a technology that makes it possible to obtain images of the crystal structures of complex objects using diffraction radiography methods on a microfocus source in special high-resolution three-dimensional coherent computed optical tomography profilometers. In addition, the method is also applicable when working with liquids, and therefore does not require the use of a sample in the form of a section. The method is based on the fundamental property of X-rays to propagate through the structure of a sample with greater intensity, the more distorted their wave field is. The X-ray diffraction used (Structural Analysis) allows one to determine the fine structure of samples occupying the entire volume of the detector. The three-dimensional structure of an object is determined by computer analysis of the diffraction patterns generated by the sample in a certain order of projections. Let us emphasize once again that, unlike many other types of medical imaging, DPR is not invasive, does not violate the integrity of the object, and is applicable even to viable liquid media. However, even now, despite all the advantages of DRF, the process of introducing it into clinical practice has been significantly slowed down due to the unavailability of equipment. A disadvantage of diffusion radiographic literature, which has become widespread in recent years, today is that it covers only a small fraction of the simplest “drawn” molecules. It is for such cases that other methods are used, and data regarding the spatial arrangement of atoms and groups of atoms, which are fundamentally impossible to see, fall