Radioresistance is the body’s ability to withstand the effects of radiation and maintain its vital functions.
All living organisms have radioresistance, but in some it is more pronounced. For example, in plants and animals it is less pronounced than in humans. In humans, it can be either congenital or acquired. Congenital radioresistance is determined genetically, and acquired resistance is determined by living and working conditions.
Radioresistance is an important property of an organism, as it allows it to survive under radiation conditions. It helps the body protect itself from harmful influences and maintain its normal functioning. However, if there is no radioresistance, then the body may be exposed to great risks and even die.
In medicine, radioresistance is of great importance in the treatment of cancer. Radiotherapy is used to treat cancer, and radioresistant tumors respond better to treatment than radiosensitive tumors. This is because radioresistant cells are more resistant to radiation and can only be killed by high doses of radiation.
Radioresistant tumors are types of tumors that are resistant to treatment with radioactive radiation. Radiosensitive drugs include platinum-, silver-, gold-containing drugs, daunorubicin, cyclophosphamide, methotrexate and many others. The degree of tumor radioresistance is assessed by the size of the tumor after previous radiation therapy. A distinction is made between true radioresistance and false resistance - which develops in patients who have not received radiation therapy at all, or who have received too little radiotherapy for a true radioresistant tumor to manifest.