Erythrocyte sedimentation reaction

The erythrocyte sedimentation test (ERS) is a laboratory test that is used to determine the sedimentation rate of red blood cells in the blood. This analysis helps to identify the presence of inflammatory processes in the body and diagnose various diseases.

The process of ROE occurs as follows: red blood cells, which have a negative charge, are attracted to negatively charged particles of proteins found in the blood plasma. These proteins are called fibrinogen, and they play an important role in blood clotting during injury or other damage. When red blood cells settle on these proteins, it is called a sedimentation reaction.

The erythrocyte sedimentation rate is measured in millimeters per hour. The higher the ROE indicator, the greater the likelihood of an inflammatory process in the body. A high level of ROE can be associated with various diseases, such as rheumatoid arthritis, infectious diseases, cancer and others.

To conduct an analysis for ROE, you need to take a small amount of blood from a vein and place it in a special container. The container is then placed in a centrifuge where the blood is subjected to centrifugal force. This causes the red blood cells to settle at the bottom of the container while the plasma remains on top. After centrifugation, the height of formation of the erythrocyte sediment is measured, which makes it possible to determine the level of ROE.

In conclusion, erythrocyte sedimentation test is an important test that helps in diagnosing various diseases and monitoring health status. If the ROE level increases, you should consult a doctor for additional research and treatment.

Introduction. The erythrocytosis sedimentation reaction is one of the important diagnostic methods for human blood tests. It allows the doctor to evaluate many diseases using certain indicators characterizing red blood cells. Sedimentation is characterized by the ability of blood to form elements in it - lumps. The method is based on the separation of blood fractions by settling whole blood cells (erythrocytes, leukocytes and platelets) to the bottom of a vessel or test tube. This method is more convenient for blood testing compared to others, and also has additional advantages - sedimentation results in different test tubes can be characterized less differently. In medical laboratories, it is performed to detect inflammatory processes (leprosy, brucellosis), allergic diseases, pathologies of the coagulation system (liver disease), and severe cardiovascular pathologies. It doesn't take long to get results.

General information about the erythrocyte sedimentation reaction (ESR), what is this indicator? This is an outdated term. Nowadays the abbreviation is more often used: ESR (Sedimentation/Sedimentation Rate).

Subsidence occurs due to the attraction of the Earth's magnetic field. Moreover, various iron compounds contained in the blood (for example, erythrocyte iron) begin to fall first, because they have high magnetic susceptibility. Under the influence of this natural phenomenon, all components of the blood float under the influence of gravity. The result of the study shows this movement as sedimentation of red blood cells.

The final result is influenced by the type of biomaterial being studied, the patient’s condition, time of year, and time of day. But in general, according to the table values ​​​​in the laboratory, indicators within 3-8 hours are considered normal.

Conclusion. Thus, the sedimentation reaction is one of the most effective and informative diagnostic methods in determining many diseases. The speed of this reaction is directly proportional to the various manifestations of the physiological or pathological state of the patient’s body.