Reticulocytosis

Reticulocytosis is a condition characterized by an increase in the number of immature red blood cells, called reticulocytes, in the circulating blood.

Reticulocytes are young red blood cells that have recently formed in the bone marrow and have not yet reached maturity. Typically, reticulocytes make up about 1% of the total number of red blood cells.

An increased level of reticulocytes in the blood (reticulocytosis) indicates activation of hematopoiesis in the bone marrow in response to the body's increased need for red blood cells. This can occur in various conditions accompanied by hemolysis (destruction of red blood cells) or blood loss, for example, anemia, bleeding, hemolytic crises with hemolytic anemia.

Thus, the detection of reticulocytosis has diagnostic value, indicating increased hematopoiesis and being a marker of the regenerative response of the bone marrow to anemia. Quantitative assessment of reticulocytes is important for monitoring the course of diseases of the blood system.



Reticulocytes are young red blood cells that are formed in the red bone marrow and released into the blood. When the body encounters iron deficiency or other factors that can cause anemia, the bone marrow begins to produce more red blood cells to compensate for the lack of iron.

However, if the number of red blood cells increases too quickly, it can cause the bone marrow to be unable to keep up with producing enough mature cells. In this case, the bone marrow will continue to produce young cells, and the level of reticulocytes in the blood will increase.

Reticulocytosis can be caused by various reasons, such as:

– Anemia caused by iron deficiency;
– Infectious diseases such as malaria and tuberculosis;
– Chronic kidney or liver diseases;
– Inflammatory processes in the body;
– Pregnancy;
– Taking certain medications, such as corticosteroids and anticancer drugs.

If your reticulocyte count rises, it may indicate that the body is trying to compensate for iron deficiency or other factors causing anemia. However, if reticulocyte levels remain high for a long time, it may indicate the presence of other diseases or health problems.

To determine the level of reticulocytes, you need to take a blood test. If your reticulocyte count is elevated, it may be a sign of anemia or other medical conditions, so it is important to see a doctor for diagnosis and treatment.



Reticulocytes are young red blood cells. They contain a nucleus and less hemoglobin than mature red blood cells and cannot carry oxygen to tissues and organs. Unlike maturing young cells, they are not captured by the spleen and liver.

The growth, maturation, reproduction and destruction of red blood cells occur in the bone marrow. Typically, there are about 5 mature forms of red blood cells circulating in the body. The remaining cells die, and they also penetrate the walls of blood vessels and are captured by tissues and organs. When the body's need for oxygen increases, the bone marrow begins to produce new mature forms of red blood cells to replace those that die.