Reticuloendotheliocyte Stellate

**Reticuloendothelial stellate cells (RES)**

Reticular endothelial stellate cells, or Kupffer cells (KCs), are phagocytic epithelial cells that line the peritoneal cavity and are involved in the regulation of immunogenesis. RES are normally present in the epithelial tissue of the liver, lungs, intestines and spleen, although they are almost invisible in healthy people. But, revealing themselves during inflammation, these cells change their size from microscopic to macroscopic. Cellular changes can help distinguish between normal and inflammatory responses, allowing them to be used as one of the markers and biomarkers of disease. The most common diseases associated with immune imbalance and migration of RES into organs are autoimmune, inflammatory, infectious diseases, infiltrative neoplasms, and malignant neoplasms.

RES are actively involved in many processes in our body. These cells are able to absorb any infectious agents and phagocytose tumor cells. Moreover, they play a key role in the metabolism of various compounds, such as lipids, metabolic metabolites. The work of Kupffer cells is not only the main mechanism of the body’s immune response to interstitial

Reticuloednotheliocytes stellate are blood cells located in the pulmonary artery of mammals. These cells play an important role in antiallergic mechanisms and are one of the components of the body's defense against infections. They are involved in regulating the immune response by releasing various signaling molecules such as cytokines, which allows them to function as parts