Resorption1

Resorption

Resorption (Latin resorbtio, from resorbeo - absorb, absorb) in pathology is the process of resorption and destruction of cellular elements and intercellular substance that occurs in the tissues of the body.

Resorption most often has a pathological nature and is accompanied by a decrease in volume or complete disappearance of tissue structures. For example, resorption of bone tissue leads to the development of osteoporosis, resorption of cartilage tissue leads to the development of arthrosis.

The mechanism of resorption is the activation of lysosomal enzymes, which destroy cellular structures. Factors that cause resorption include inflammation, impaired blood supply, mechanical pressure, tumor growth, etc.

Resorption can be reversible (when the cause is eliminated) and irreversible (leading to irreparable loss of tissue). Understanding the mechanisms of resorption is important for developing methods for its prevention and treatment of diseases accompanied by resorptive changes in tissues.

A resorptive reaction is a normal physiological process of restoration of the body by absorbing components of the intercellular substance and their subsequent transfer to the area of ​​tissue damage for the purpose of its healing. Resorbing tissue reactions underlie the processes of epithelization, hyalinization and repair of interstitial tissue, tissue retraction on damaged surfaces of cartilage and bone or around defective bone and cartilage, as well as a number of other natural wound healing processes in the absence of disruption of the skin (“secondary wounds”). .