Scleroderma, or scleroderma, is a chronic autoimmune connective tissue disease characterized by progressive systemic sclerosis of the skin, blood vessels and internal organs.
With scleroderma, pathological compaction and thickening of the connective tissue occurs due to the accumulation of collagen in it. This process can involve the skin, heart, lungs, kidneys, esophagus and other organs. The skin thickens, becomes dense, inelastic and acquires a waxy pale pink or whitish color.
There are localized and systemic forms of the disease. With localized scleroderma, the lesions are limited only to the skin, and with the systemic form, the process affects the internal organs and the musculoskeletal system.
Scleroderma is a chronic, progressive disease that in severe cases can lead to disability and death. No radical treatment methods have been found yet, but modern therapy can slow down the development of the disease and alleviate its manifestations.